“ Detection of rEPO Abuse in Athletes ”

نویسندگان

  • M. Magnani
  • P. Pigozzi
چکیده

In order to improve their performance, some athletes utilize methods which optimize the physiological characteristics needed for their sport. The considerable availability of recombinant human erythropoietin (rEPO) has allowed the widespread use of this drug in aerobic sports to increase oxygen transfer capacity. Like endogenous EPO the recombinant hormone interacts with the precursor erythroid cells causing proliferation and differentation of these cells in mature erythrocytes (1). Although rEPO has banned by the medical commission of the International Olympic Committee, the anti-doping tests currently available cannot detect it with confidence. A direct detection of rEPO in urine has recently been suggested (2).

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تاریخ انتشار 2010